Retatrutide (LY3437943) is a next-generation synthetic peptide engineered as a triple receptor agonist targeting GLP-1, GIP, and glucagon receptors. Its innovative molecular design distinguishes it from earlier single- and dual-receptor peptide technologies, making it one of the most widely studied compounds in contemporary metabolic research.
Supplied as a high-purity lyophilized powder, Retatrutide offers excellent stability for laboratory handling, transportation, and long-term storage. It is commonly utilized in scientific investigations involving receptor signaling, metabolic regulation, peptide engineering, and endocrine research.
✔ High Purity (≥98% HPLC)
✔ White to Off-White Lyophilized Powder
✔ Excellent Stability for Research Applications
✔ Triple Receptor Agonist Technology
✔ Strict Quality Control and Batch Consistency
✔ Suitable for Advanced Peptide Research
| Item | Specification |
|---|---|
| Product Name | Retatrutide |
| Synonym | LY3437943 |
| Molecular Formula | C221H342N46O68* |
| Molecular Weight | Approximately 4731 Da* |
| Appearance | White Lyophilized Powder |
| Purity | ≥98% by HPLC |
| Storage | -20°C Recommended |
| Solubility | Water Soluble |
| Application | Laboratory Research Only |
*Specifications may vary according to manufacturing batch and analytical standards.
| Product Name | CAS Number |
|---|---|
| AOD-9604 | 221231-10-3 |
| BPC-157 | 137525-51-0 |
| PT-141 / Bremelanotide Acetate | 189691-06-3 |
| CJC-1295 | 863288-34-0 |
| GHK-Cu | 89030-95-5 |
| GHRP-2 | 158861-67-7 |
| Hexarelin | 140703-51-1 |
| IGF-1 LR3 | 946870-92-4 |
| Ipamorelin | 170851-70-4 |
| KPV / Alpha MSH (11-13) | 67727-97-3 |
| L-Arginine | 74-79-3 |
| MOTS-C | 1627580-64-6 |
| Oxytocin | 50-56-6 |
| PDA | 106-50-3 |
| Selank | 129954-34-3 |
| Semax | 80714-61-0 |
| Sermorelin | 86168-78-7 |
| SS-31 (Lyo) / Elamipretide | 736992-21-5 |
| TB500 Fragment | 476014-70-7 |
| Tesamorelin | 218949-48-5 |
| Thymogen / Oglufanide | 38101-59-6 |
| Thymosin Alpha-1 / Thymalfasin | 62304-98-7 |
| Thymosin Beta-4 | 77591-33-4 |
| TB500 | 885340-08-9 |
| NVG-291 | 2135482-62-7 |
| CB4211 | 2361287-87-0 |
| DSIP | 62568-57-4 |
| Epitalon | 307297-39-8 |
| Gonadorelin | 33515-09-2 |
| LL-37 | 154947-19-0 |
| Melanotan II | 121062-08-6 |
| MK-0616 | 2249825-14-7 |
| NAD+ | 53-84-9 |
| Pamorelin | 57773-63-1 |
| PTD-DBM | 1241682-11-0 |
| Fragment 176-191 | 66004-57-7 |
| VIP | 40077-57-4 |
| PE-22-28 | 1136689-11-0 |
Retatrutide is designed to simultaneously activate three metabolic hormone receptors:
Associated with appetite regulation, gastric emptying pathways, and glucose-related signaling mechanisms.
Involved in nutrient sensing, insulin signaling, and metabolic regulation processes.
Linked to energy expenditure, lipid metabolism, and metabolic adaptation pathways.
The combined activation of these three receptor systems makes Retatrutide a unique research compound for investigating complex metabolic interactions and multi-pathway biological responses.
Retatrutide has become an important subject in several areas of scientific research, including:
Researchers continue to explore its unique triple-agonist profile and its potential implications for future peptide development.
Every batch of Retatrutide should undergo rigorous analytical testing, including:
A Certificate of Analysis (COA) can be provided upon request to ensure product quality and traceability.
To maintain optimal peptide stability:
Long-Term Storage
After Reconstitution
Proper storage conditions help preserve peptide integrity and analytical performance.
Available packaging options may include:
Bulk quantities and OEM packaging services are available for qualified research organizations.
Retatrutide is supplied strictly for laboratory research and analytical purposes only. This product is not approved for human consumption, medical use, therapeutic application, or diagnostic procedures. Researchers are responsible for ensuring compliance with all applicable regulations and institutional guidelines.